Japan's Nikkei index fell as the yen strengthened against the dollar, while retailer Seven & I Holdings jumped 23% after receiving a takeover offer.
The Nikkei index closed down 1.77% at 37,388.62 points, ending a five-day winning streak that had seen the index rise 8.7% last week.
Dollar Index and Jackson Hole Awaiting
The dollar fell in general and fell sharply against the yen in particular, amid traders' expectations that the minutes of the US Federal Reserve's July meeting would show a dovish tone, in addition to anticipation of the speech by Federal Reserve Chairman Jerome Powell scheduled in Jackson Hole.
Chip-making equipment maker Tokyo Electron lost 3.11%, dragging the Nikkei lower, while robot maker Fanuc lost 3.23%.
Seven & I Holdings Inc. bucked the trend, jumping 23% to a daily high after the company, which operates the 7-Eleven convenience store chain in the country, said it had received a preliminary takeover offer from Canada's Alimentacion Cos-Tar.
Seven & I said it had formed a special committee to review the offer, but the committee and the board had not made any decisions.
Of the 225 stocks listed on the Nikkei index, 191 fell, 22 rose and one was flat.
The broader Topix index fell 1.4% to 2,641.14, with Toyota Motor Corp falling 3.06%.